|Management of tendinopathies and tendon rupture is challenging.
In the last few decades, several emerging strategies including tissue engineering with mesenchymal stem cells have been proposed to enhance tendon healing.
They hold the promise to yield more successful outcomes for the management of patients with tendon pathology.
Current in vitro studies support the application of these cell-based therapies for the regeneration of tendon tissues. However, these cell-based strategies have been investigated only in pre-clinical studies and the role of stem cells needs to be confirmed. We performed a review of the literature to focus on actual knowledge and the future perspectives of stem cells for tendon regeneration and tendon engineering.
Stem cells and tendinopathy: state of the art from the basic science to clinic application
Ruzzini L., Longo U.G., Rizziello G., Denaro V.
Mini-Review, 235 - 238
Keywords: mesenchymal stem cells, tendinopathy, tendon, tendon stem cells,
Table of Content: Vol. 2 (No. 3) 2012 July/September
Berardi A. C., Oliva F.Editorial, 153
Po Yee Lui P., Wong O.T.Review Article, 163 - 168
Delaine-Smith R.M., Reilly G.C.Review Article, 169 - 180
Muttini A., Salini V., Valbonetti L., Abate M.Review Article, 187 - 192
Filomeno P., Dayan V., Tourino C.Review Article, 204 - 211
The role of microvesicles derived from mesenchymal stem cells in tissue regeneration; a dream for tendon repair?Tetta C., Consiglio A.L., Bruno S., Tetta E., Gatti E., Dobreva M., Cremonesi F., Camussi G.Review Article, 212 - 221
Chaudhury S.Review Article, 222 - 229
Rizzi R., Bearzi C., Mauretti A., Bernardini S., Cannata S., Gargioli C.Review Article, 230 - 234
Ruzzini L., Longo U.G., Rizziello G., Denaro V.Mini-Review, 235 - 238
Raggi C., Berardi A. C.Mini-Review, 239 - 242