|The structure of a tendon is an important example of complexity of ECM three-dimensional organization.
The extracellular matrix (ECM) is a macromolecular network with both structural and regulatory functions. ECM components belong to four major types of macromolecules: the collagens, elastin, proteoglycans, and noncollagenous glycoproteins.
Tendons are made by a fibrous, compact connective tissue that connect muscle to bone designed to transmit forces and withstand tension during muscle contraction. Here we show the ultrastructural features of tendon’s components.
Tresoldi I., Oliva F., Benvenuto M., Fantini M., Masuelli L., Bei R., Modesti A.
Original Article, 2 - 6
Keywords: collagen, extracellular matrix., tendon, ultrastructure,
Table of Content: Vol. 3 (No. 1) 2013 January/March
Tendon’s ultrastructureTresoldi I., Oliva F., Benvenuto M., Fantini M., Masuelli L., Bei R., Modesti A.Original Article, 2 - 6
Relationship between compressive loading and ECM changes in tendonsDocking S., Samiric T., Scase E., Purdam C., Cook J.Original Article, 7 - 11
Specialisation of extracellular matrix for function in tendons and ligamentsBirch H.L., Thorpe C.T., Rumian A.P.Review Article, 12 - 22
Nanomechanics of collagen microfibrilsVesentini S., Redaelli A., Gautieri A.Original Article, 23 - 24
Muscle extracellular matrix degradation and contractibility following tendon rupture and disuseZhang Q., Joshi S.K., Manzano G., Lovett D.H., Kim H.T., Liu X.Original Article, 35 - 41
Tendon structure and extracellular matrix components are affected by spasticity in cerebral palsy patientsGagliano N., Menon A., Martinelli C., Pettinari L., Panou A., Milzani A., Dalle-Donne I., Portinaro N.M.Original Article, 42 - 50
Metalloproteases and tendinopathyDel Buono A., Oliva F., Osti L., Maffulli N.Review Article, 51 - 57