Sonophoresis with Nanostructured Lipid Carrier Gel Containing Quercetin for Muscle Injury Treatment in Rats

SUMMARY Background. Quercetin has therapeutic potential in the recovery of musculoskeletal injuries, but orally, this polyphenol presents poor absorption because of its poor water solubility and structural instability. However, its penetration through the skin can be enhanced by quercetin-loaded nanostructured lipid carriers (NLC-Q), even more, when associated with pulsed therapeutic ultrasound (PUT). Objective. To evaluate … Continued

Circulating Levels of microRNA-122 and Weight Change in Response to Combined Exercise Interventions In Metabolic Syndrome

SUMMARY Background. The study aimed to assess the combined exercise effects of the Circulating Levels of microRNA-122 and weight Change in men with metabolic syndrome (MeS). Methods. Forty men with MetS according to International Diabetes Federation criteria were randomized interventional and control groups. We investigated the effect of 12 weeks combined exercise on Levels of … Continued

Extracorporeal Shockwave Therapy in Greater Trochanteric Pain Syndrome: A Systematic Review and Meta-Analysis

SUMMARY Background. Greater Trochanteric Pain Syndrome (GTPS) poses significant challenges in clinical management due to its multifactorial etiology and limited treatment options. Extracorporeal Shockwave Therapy (ESWT) has emerged as a promising intervention in the recent past. This review aimed to evaluate the clinical efficacy of ESWT in managing GTPS symptoms. Methods. Systematic searches were conducted … Continued

Comparative Efficacy of Exercise Therapy versus Non Steroidal Anti-Inflammatory Drugs in Treating Lateral Epicondylitis

SUMMARY Aim and background. Lateral epicondylitis (LE), commonly known as tennis elbow, is characterized by pain and reduced elbow function due to overuse of the extensor carpi radialis brevis (ECRB) muscle. This study evaluates the effectiveness of exercise therapy in improving grip strength and electromyography (EMG) patterns of the ECRBmuscle in LE patients. Materials and … Continued

Histopathological Changes of Extensor Digitorum Longus Muscle Following Sciatic Nerve Transection: The Role of Mast Cells and Mesenchymal Stem Cells

SUMMARY Objectives. Damage caused by the sciatic nerve transection leads to histopathological changes of related skeletal muscles such as atrophy, necrosis, etc. In this study, these changes and ameliorative effects of using mast cells and mesenchymal stem cells along with collagen gel scaffold at the nerve’s transection site were evaluated. Methods. For this purpose, 90 … Continued

Change in Polygon Shapes of Atrophic and Small Angular Fibers in Disuse Muscle Atrophy

SUMMARY Background. Muscle fiber (MF) cross-sectional area (CSA) and muscle strength are reduced in disuse muscle atrophy (DMA). However, whether approximate shapes of MF cross-section (AS-MFCS) are altered in DMA remains unknown. This study aimed to determine the AS-MFCS of atrophic MFs. Methods. Eleven-week-old male Wistar rats were divided into control (CON) and sciatic nerve … Continued

Development and Validation of the Musculoskeletal Health Questionnaire (MSK-HQ) on an Italian Population of Padel and Tennis Players: A Cross-Sectional Study

SUMMARY Introduction. In racquet sports, players are particularly prone to a variety of musculoskeletal issues due to the repetitive and high-intensity nature of their movements, which can lead to overuse injuries, acute trauma, and chronic conditions. The Musculoskeletal Health Questionnaire (MSK-HQ) is a comprehensive tool designed to assess a wide range of musculoskeletal health parameters, … Continued

Acute Structural Repercussions of Vertical Ladder Training on the Muscle Belly of Wistar Rats after Joint Immobilization

SUMMARY Background. Resistance training promotes positive musculoskeletal adaptations that reverse changes in long-term muscle atrophy, elucidating the progression and coordination of acute muscle remodeling caused by resistance training without additional load. Objective. The aim was to describe the morphological changes and the acute period of remodeling in the gastrocnemius muscle, after muscular atrophy caused by … Continued

Effect of the Low Pressure Fitness (LPF®) Technique on Diastasis Recti Abdominis in Postpartum Women: Protocol for A Blinded Randomized Clinical Trial

SUMMARY Introduction. In the postpartum period, the female body undergoes hormonal, anatomical, and physiological changes that can negatively impact musculoskeletal health and lead to conditions such as Diastasis Recti Abdominis. Low Pressure Fitness (LPF®) has been used in clinical practice; however, there is still no consensus on its effects on the abdominal wall and whether … Continued

Relationship Between the Use of Androgenic- Anabolic Steroids and the Incidence of Myoarticular Injuries

SUMMARY Purpose. Androgenic-anabolic steroids (AAS) are a group of hormones that include testosterone and its synthetic derivatives. AAS are widely used for performance enhancement or aesthetic purposes. The use of these substances is well known for causing several negative effects on the cardiovascular system and the hypothalamic-pituitary-gonadal axis, among other systems. However, the effects on … Continued