SUMMARY
Background. Tendon injuries are difficult to heal properly, and many researchers have attempted to overcome this problem using various approaches.
Materials and methods. The authors evaluated the capabilities of Morus nigra, a widely known plant with many verified therapeutic properties, on injured tendons in the early stages of recovery.
Results. The extract did not demonstrate many benefits regarding tendon resistance to applied forces during either phase; however, an increase in the tendon capacity to stretch without rupture was observed in the early stages of repair. The leaf extract visibly accelerated the recovery process after 15 days of treatment, altering the profile of collagen/GAG deposition in the tendons, reducing inflammatory infiltrate and cellularity, with an increase in all MMP-2 forms expression.
Conclusions. The leaf extract accelerated the recovery of tendon morphology. Further studies to identify molecule-specific mechanisms could prove beneficial for tendon healing.
Healing Effect of Morus nigra Leaf Extract over Tendon Injuries on Proliferative Phase
Luiza Oliveira Borges, Rafael Junio Ribeiro, Teresa Maria Da Ré Silva, Flávia Da Ré Guerra, Petrus Pires Marques
Original Article, 558-563
Keywords: biomechanics, healing, Morus nigra, phytotherapy, tendinopathy, tendon injury,
Table of Content: Vol. 13 (No.4) 2023 October/December
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