Background. The effect of non-steroidal anti-inflammatory drugs (NSAIDs) on recovery after Achilles tendon rupture is unknown. This is the first study examining the relationship between NSAID use and recovery after Achilles tendon rupture in humans.
Methods. Adult patients presenting between 01/01/14 and 03/30/2018 with acute Achilles tendon rupture were asked to complete a survey in the Spring of 2018 to determine whether they took NSAIDs after rupture. Their recovery was quantified in three ways: 1) the Achilles Tendon Total Rupture Score (ATRS), 2) the duration of time to walk again normally, and 3) the incidence of tendon re-rupture. Recovery was compared across NSAID and non-NSAID users.
Results. Fifty-three percent of 361 patients who completed the survey used NSAIDs following tendon rupture. NSAID users reported a significantly lower ATRS (69) than non-NSAID users (77; p < 0.005). There was no difference in time to walk again normally or incidence of re-rupture. After controlling for age, sex, operative versus non-operative treatment, and time from diagnosis to survey completion, NSAID use was still associated with a significantly lower ATRS (p = 0.003).
Conclusion. NSAID use was associated with a lower ATRS after Achilles tendon rupture.
Non-Steroidal Anti-Inflammatory Drug Use and Recovery after Achilles Tendon Rupture
V. Franco, J. Grotts, J. C. Lin, M. K. Fong, M. S. Vasquez
Original Article, 314-321
Keywords: ATRS, healing, inflammation, musculoskeletal,
Table of Content: Vol.9 (No.3) 2019 July/September
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Efficacy of ultrasound-guided hyaluronic acid injections in achilles and patellar tendinopathies: a prospective multicentric clinical trial
A. Frizziero, F. Oliva, F. Vittadini, M. Vetrano, A. Bernetti, N. Giordan, M.C. Vulpiani, V. Santilli, S. Masiero, N. MaffulliOriginal Article, 305-313 -
Non-Steroidal Anti-Inflammatory Drug Use and Recovery after Achilles Tendon Rupture
V. Franco, J. Grotts, J. C. Lin, M. K. Fong, M. S. VasquezOriginal Article, 314-321 -
Comparison between platelet-rich plasma injections and hyaluronic acid injections in the treatment of patellar tendinopathies: a randomized trial
J.-F. Kaux, S. Bornheim, N. Dardenne, R. Deroisy, A. Samson, M. Roberjot, J.-L. CroisierOriginal Article, 322-327 -
Comparison of ultrasound-guided versus blind interventions for supraspinatus tendinopathy: a cadaveric study
F. Abat, J. Campos, J. Torras, M. Madruga, G. Planells , A. Rodriguez-BaezaOriginal Article, 328-337 -
Healing of partial-thickness rotator cuff tears following arthroscopic augmentation with a highly-porous collagen implant: a 5-year clinical and MRI follow-up
D. J. Bokor, D. H. Sonnabend, L. Deady, B. Cass, A. A. Young, C. L. Van Kampen, S. P. ArnoczkyOriginal Article, 338-347 -
Reliability of an isometric and isokinetic strength testing protocol of the knee and ankle in young adults
S. Gobbo, M. Bergamin, V. Bullo, M. Bergamo, D. S. Bocalini, A. di Blasio, L. Cugusi, E. Roma, F. Battista, C. L. Alberton, D.l Neunhaeuserer, A. Frizziero, B. Vendramin, F. Duregon, A. ErmolaoOriginal Article, 348-355 -
Quadriceps tendon rupture. Anchor or transosseous suture? A systematic review
M. Corÿdon Hochheim, E. M. Bartels, J. Vestergård IversenReview, 356-362 -
Post-traumatic ankle osteoarthritis: quality of life, frequency and associated factors
R. D’Ambrosi, C. Di Silvestri, L. Manzi, C. Indino, C. Maccario, F.G. UsuelliOriginal Article, 363-371 -
Morphological variants of pes anserinus in South India
B.V. Murlimanju, R. Vadgaonkar, C. Ganesh Kumar, M.D. Prameela, M. Tonse, M. M. Pai, V. BlossomOriginal Article, 372-378 -
Does the 5-strand-graft have superior biomechanical behaviour than 4-strand-graft during ACL reconstruction?
D. Pavan, G. Pitarresi, F. Morello, F. Monachino, A. Sanfilippo, A. D’Arienzo, L. CamardaOriginal Article, 379-385 -
Influence of Cleat Design on Knee Joint Moments During Cutting Maneuver and Instep Kick in Soccer
W. Rosa de Olivera, A. N. Onodera, M. La TorreOriginal Article, 386-394 -
Relationships between cardiovascular disease risk factors and Achilles tendon structural and mechanical properties in people with Type 2 Diabetes
B.K. Coombes, K. Tucker, F. Hug, A. Scott, M. Geytenbeek, E.R. Cox, T. Gajanand, J.S. CoombesOriginal Article, 395-404 -
Treatment of infections of the lumbar spine with single-staged posterior instrumentation, disc debridement and interbody fusion with titanium cages
D. Cucchi, L. Deharde, A. Kasapovic, M. Gathen, Y. Rommelspacher, R. Bornemann, D. C. Wirtz, R. PflugmacherOriginal Article, 405-416 -
B mode, Doppler and ultrasound elastography imaging on active trigger point in women with myofascial pain syndrome treated by dry needling
H. Adigozali, A. Shadmehr, E. Ebrahimi, A. Rezasoltani, F. NaderiOriginal Article, 417-424 -
Regression model for the prediction of risk of sarcopenia among older adults
T. Agnes, K.Vishal, Girish NOriginal Article, 425-432 -
Electromyostimulation and whole-body vibration effects in elder sarcopenic patients
E. Chisari, V. Pavone, G. Sessa, S. Ravalli, G. MusumeciOriginal Article, 433-441 -
Influence of duration of pain on postural sway in individuals with mechanical neck pain
K. Vishal, A. Walkay, T. Huixin, Y. V. Raghava Neelapala, V. Suresh BhatOriginal Article, 442-445 -
Combined Anatomic Reconstruction of the Anterior Cruciate and Anterolateral Ligaments, How I do it
N. Maffulli, P. Colombet, F. Oliva, A. OlivieroOriginal Article, 457-462 -
Neuromuscular electrical stimulation associated with core stability exercises in nonspecific postural low back pain: a randomized clinical trial
R. Dimer da Luz, M. da Silva Santos, A. Steffen Evaldt, L. da Silva Matos, R. Boff Daitx, M. B. DöhnertOriginal Article, 446-456 -
Evaluation of Concentrated Bone Marrow-derived Mesenchymal Stem Cells Produced from Two Different Cellular Concentrating Systems
J. M. Brewer, M. B. McCarthy, L. Pauzenburger, M. P. Cote, A. D. MazzoccaOriginal Article, 463-469