Morphological Changes and Pathological Findings in the Achilles Tendons of Diabetic Patients: A Meta-Analysis of Comparative Clinical Studies

SUMMARY Objective. There is a greater risk of tendon rupture requiring hospitalization in people with diabetes. Diabetes could induce substantial alteration in Achilles tendon (AT) that could affect its mechanical properties mainly in relation to gait and foot ulceration. Many studies reported AT morphological changes using diagnostic methods in clinical settings. However, there is no quantitative synthesis of the published … Continued

TGF-ß1 Expression in Contractured Achilles Tendon among Diabetic Foot Patients: a Semi-Quantitative Study

SUMMARY Background. Increased plantar pressure when walking is among the pathogenesis of diabetic foot ulceration. Contractured Achilles tendon will biomechanically results in increased plantar pressure. In this study, we summarize the correlation between increased transforming growth factor β1 (TGF-β1) expression and the development of Achilles tendon contracture in diabetic foot patients. Methods. Thirty diabetic foot patients with indication for … Continued

Identifying Differences in Elastographic Properties of Calf Muscles and Tendons Across Subsets of Tennis Players

SUMMARY Objective. Calf strain occurs frequently in tennis players and has been termed “tennis leg”. To date, there is a lack of information showing how injury history, age, gender, or level of play, may predispose tennis players to injury (1, 2). The purpose of this study was to investigate the elastographic properties of the gastrocnemius-soleus complex in a group … Continued

Patient-Reported Outcome and Healing Biomarkers in Patients Treated by Female versus Male Surgeons – A cohort study on Achilles tendon ruptures

SUMMARY Background. Woman and men practice medicine differently. One recent study showed that patients operated on by female surgeons exhibited better outcome. We hypothesized that the sex of the surgeon would not affect patient outcome, adverse events and the biological processes of healing after surgical repair of Achilles tendon rupture (ATR). Methods. A total of … Continued

Quantifying the Dimensions of Achilles Tendon Insertional Area Using Ultrasound Imaging A Validity and Reliability Study

SUMMARY Background. The purpose of this study was to evaluate the reliability and validity of using US imaging for measuring Achilles tendon insertion area to the calcaneus. Methods. Sixteen cadaveric tendons were used to compare the agreement between Achilles tendon insertion length measurements from US images with actual measurements after dissection. In addition, test-retest reliability … Continued

Efficacy of ultrasound-guided hyaluronic acid injections in achilles and patellar tendinopathies: a prospective multicentric clinical trial

Background. Achilles and patellar tendinopathies are common causes of chronic pain and functional impairment. Conservative management can be effective, but it is time-consuming and it requires intensive patient compliance. Hyaluronic acid (HA) is a key component of the extracellular matrix and its anti-inflammatory, lubricant and analgesic properties are well documented in osteoarthritis. Growing pre-clinical studies … Continued

Extracorporeal Shockwave Therapy of Healthy Achilles Tendons Results in a Conditioned Pain Modulation Effect: A Randomised Exploratory Cross-Over Trial

Background. This study investigated whether ESWT applied to healthy Achilles tendons results in a conditioned pain modulation (CPM) effect. Methods. 3000 and 6000-shock dose radial ESWT was performed on dominant side Achilles tendon (random order over 5-9 days) among 20 healthy participants (75% male). Pressure was modulated throughout, producing >4/10 pain (10=worst imaginable). Bilateral pressure-pain … Continued