Tag: animal model

Perfecting Achilles Tendinopathy Inducement: Preliminary Study in Animal Model – BONAR Score as Quantitative Indicator

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SUMMARY Background. As a common ailment suffered by runners and athletes, Achilles tendinopathy pathogenesis is not well understood. To reveal its cellular and molecular changes, universal and standardized method to induce Achilles tendinopathy in animal model (in vivo) study should be established. There are 2 major guidelines to induce Achilles tendinopathy: run the rats on … Continued

Inflammatory Response of Skeletal Muscles to a High-Fat Diet

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SUMMARY Background. The prolonged consumption of a high-fat diet (HFD) leads to abnormal growth of the adipose tissue, development of obesity and low-grade inflammation. However, the data about dietary-induced inflammation in muscles is scarce. Therefore, we estimated the inflammatory response to a HFD of different skeletal muscles in a rat model. Materials and methods. Eight-week-old male Wistar rats … Continued