Adding Injectable Chitosan Poloxamer to Platelet Rich Plasma (PRP) Has no Beneficial Effect in Knee OA. A prospective Experimental Study in Guinea Pigs

SUMMARY Background. Short term symptomatic relief with single dose PRP in early knee OA has been established. We studied the effect of Chitosan as an additive to PRP, in an attempt to improve and prolong the effects. Methods. 42 Dunkin Hartley guinea pigs were divided into 4 groups of 10 each; 2 animals were used … Continued