Resveratrol Treatment Protects Tendons from Obesity and Insulin Resistance Effects

SUMMARY Background. Obesity and Insulin resistance (IR) are conditions that cause metabolic disorders and secondary effects, including musculoskeletal complications making tendon prone to lesions. Antidiabetic drugs presents several side effects, making fundamental the pursue of alternative treatments, to improve patient’s quality of life. Resveratrol (RSV) can re-establish insulin sensitivity and regulate glycemic levels. It also … Continued

TGF-ß1 Expression in Contractured Achilles Tendon among Diabetic Foot Patients: a Semi-Quantitative Study

SUMMARY Background. Increased plantar pressure when walking is among the pathogenesis of diabetic foot ulceration. Contractured Achilles tendon will biomechanically results in increased plantar pressure. In this study, we summarize the correlation between increased transforming growth factor β1 (TGF-β1) expression and the development of Achilles tendon contracture in diabetic foot patients. Methods. Thirty diabetic foot patients with indication for … Continued