Autograft Soaking in Vancomycin in Anterior Cruciate Ligament Reconstruction Alters Tendons Structure: an Histopathological Interpretation

SUMMARY Background. Anterior cruciate ligament rupture is a frequent injury in sports and infection after reconstruction is rare (0.14-1.8%). Intravenous antibiotic prophylaxis and soaking of autografts with vancomycin (tendons are soaked into a compress that contains 100ml of NaCl mixed with 500 mg of vancomycin for 10-15 min) have been applied in order to avoid infection after ACL reconstruction. … Continued