Orthobiologic Injectables in the Ankle Joint: a Narrative Review

SUMMARY Background. The ankle joint is a frequent site of injury and bone remodeling, and often requires cartilage repair. Studies have shown that growth factors and bioactive compounds have regenerative properties capable of promoting cartilage restoration. Hyaluronic acid (HA) and orthobiologics like platelet-rich plasma (PRP) and adult stem cells (ASCs) are particularly interesting as therapeutic solutions for ankle … Continued

Evaluation of Concentrated Bone Marrow-derived Mesenchymal Stem Cells Produced from Two Different Cellular Concentrating Systems

Background. Concentrated bone marrow-derived mesenchymal stem cells (concentrated bMSCs) are used to improve in-vivo healing, yet in-vivo studies do not describe the cellular components that constitute the concentrated bMSCs. If different concentrating systems create concentrated bMSCs with different cellular components this could affect in-vivo study results. This study sought to compare the cellular components of … Continued