Optimal Platelet Concentration for The Therapeutic Effect of Autologous Neutrophil-Reduced Platelet Rich Plasma in A Rat Model of Achilles Tendinopathy

SUMMARY Background. Autologous Platelet-Rich Plasma (PRP) therapy is used for treatment of tendinopathy. Efficacy, however, is variable, possibly caused by differences in PRP platelet concentrations. In an animal model of tendinopathy, we determined if there was an optimal PRP platelet concentration. Methods. Tendinopathy was induced by collagenase injections into the Achilles tendons in rats. 10 … Continued