Musculoskeletal Ultrasound Changes in Chronic Plantar Fascia after Treatment with Platelet Rich Plasma Compared to Steroid

SUMMARY Background. Chronic plantar fasciitis (PF) is a common orthopedic condition that can demonstrate hard to effectively treat. In this study, platelet-rich plasma (PRP), a concentrated bioactive blood segment wealthy in cytokines and growth factors, was compared to steroid injection in the treatment of Chronic plantar fasciitis resistant to traditional non-operative management. Objective. To compare … Continued

Orthobiologic Injectables in the Ankle Joint: a Narrative Review

SUMMARY Background. The ankle joint is a frequent site of injury and bone remodeling, and often requires cartilage repair. Studies have shown that growth factors and bioactive compounds have regenerative properties capable of promoting cartilage restoration. Hyaluronic acid (HA) and orthobiologics like platelet-rich plasma (PRP) and adult stem cells (ASCs) are particularly interesting as therapeutic solutions for ankle … Continued

No Effect of Intra-Articular Platelet-Rich Plasma Injections after Arthroscopic Repair of Rotator Cuff Tears: a Prospective Randomized Study

SUMMARY Background. Our study aims to evaluate the results of platelet-rich plasma (PRP) infil­tration after arthroscopic repair of the rotator cuff. Methods. We carried out a randomized simple blind clinical trial with an initial sample of 38 patients. Of those, three were excluded intraoperatively. These patients were assigned into two groups: rotator cuff suture with … Continued

Combining Platelet Rich Plasma and Concentrated Bone Marrow with a Demineralized Bone Matrix Scaffold Enhances Growth Factor Release Over Time

SUMMARY Background. Scaffolds composed of demineralized bone matrix (DBM) enriched with platelet rich plasma (PRP) and concentrated bone marrow-derived mesenchymal stem cells (concentrated bMSCs) may be able to release growth factors over time. The hypothesis is that the combination of PRP + bMSCs + DBM will result in high levels of growth factor release over … Continued

Neutrophil-Reduced Platelet Rich Plasma with Optimal Platelets Concentrations for Epicondylitis of the Elbow

SUMMARY Background. Autologous platelet-rich plasma (PRP) therapy has been applied in treat­ment of medial or lateral elbow epicondylitis; however, its efficacy is variable possibly due to differences in PRP platelet or neutrophil concentrations. We prepared neutro­phil-reduced PRP with optimized platelet concentrations, and investigated therapeu­tic effects of the platelet-optimized PRP for elbow epicondylitis. Methods. We treated … Continued