Concentrated Bone Marrow Aspirate and Subacromial Bursa-Derived Cells Demonstrate Similar Cellular Adhesion and Proliferation Potential on Demineralized Bone Matrix Scaffolds for Biologic Augmentation of Rotator Cuff Repair

SUMMARY Background. Specific scaffolds are still required to sufficiently deliver and retain applied mesenchymal stem cells (MSCs) of various origins to the targeted zone of repaired tissue. The purpose of the study was to evaluate the demineralized bone matrix (DBM) as a scaffold for concentrated bone marrow aspirate (cBMA), subacromial bursa-derived cells (SBDCs), tenocytes, and … Continued

Histological and Biomechanical Evaluation of Biologic Adjuvants in a Murine Tendon-Bone Healing Model

SUMMARY Background. The purpose of this study was to compare subacromial bursa to concentrated bone marrow aspirate (cBMA) in a murine, tendon-bone healing model. The authors hypothesized that subacromial bursa would show similar biomechanical, histological, and cell survivability to that of cBMA. Methods. Thirty-nine NSG mice were included in the study. All mice underwent simulated … Continued