Healing Effect of Morus nigra Leaf Extract over Tendon Injuries on Proliferative Phase

SUMMARY Background. Tendon injuries are difficult to heal properly, and many researchers have attempted to overcome this problem using various approaches. Materials and methods. The authors evaluated the capabilities of Morus nigra, a widely known plant with many verified therapeutic properties, on injured tendons in the early stages of recovery. Results. The extract did not … Continued

The Effect of L-Carnitine on Experimental Achilles Tendon Injury

SUMMARY Background. L-carnitine (LC), which has anti-inflammatory and antioxidant effect, is especially consumed by sportmans to increase muscle mass recently. Therefore, the functional, histopathological effects of LC on experimental Achilles tendon injury were investigated in this study. Methods. Forty male Wistar Albino rats were randomly divided into four groups (n = 10). A tendon injury … Continued

Evaluation of the Effect of Melatonin on the Calcaneal Tendon of Ovariectomized Wistar Rats

SUMMARY Background. The Achilles tendon is the most injured tendon in humans. There is a close relationship between changes in the structural composition of the extracellular matrix and tendon tissue related to age and menopause because estrogen deficiency can lead to decreased collagen synthesis and a consequent decrease in the strength and elasticity of tendons, … Continued

Lower-Limb Connective Tissue Morphologic Characteristics in Runners. How Do They Relate with Running Biomechanics and Tendon Pathology? A Systematic Review

SUMMARY Although the role of connective tissue in running injuries and biomechanics has been widely investigated, systematic reviews on this issue were rarely reported. The aim of this study is to systematically review the current literature regarding the morphological characteristics (i.e., cross-sectional area and thickness) of the main connective tissue of the lower limb in runners and its … Continued

Short-Term Outcome of Focused Shock Wave Therapy for Sural Myofascial Pain Syndrome associated with Plantar Fasciitis: a Randomized Controlled Trial

SUMMARY Background. This study aims to describe prevalence and clinical features of the sural myofascial pain syndrome (SMPS) in a population affected by plantar fasciitis and to investigate if a shock wave treatment extended to the gastrocnemius-soleus trigger points is more effective in speeding up the improvement of heel pain and sural myofascial pain than … Continued

Treatment of Lateral Epicondylitis with Collagen Injections: a Pilot Study

SUMMARY Background. Lateral epicondylitis, or tennis elbow, is the prevalent cause of elbow pain among adults. Collagen injections are used to treat different musculoskeletal disorders. Type I porcine collagen has proved to enhance tendon repair in vitro. Aims of the present pilot study were to verify the effects of type I porcine collagen injections on … Continued

Relationships between cardiovascular disease risk factors and Achilles tendon structural and mechanical properties in people with Type 2 Diabetes

Background. Patients with diabetes have 44% greater risk of tendon rupture requiring hospitalisation. Despite this, in vivo research of the associations of diabetes and other cardiovascular disease risk factors on structural and mechanical properties of the Achilles tendon are sparsely studied. Methods. Inactive individuals with type 2 diabetes (n=33) underwent ultrasound and shear wave elastography … Continued

Comparison between platelet-rich plasma injections and hyaluronic acid injections in the treatment of patellar tendinopathies: a randomized trial

Background. As patellar tendinopathies are frequently chronic there has been plenty of research carried out to develop effective treatments, among which platelet-rich plasma (PRP) and hyaluronic acid (HA). Hypothesis. Therefore we aimed to compare the effect after three months following injections of PRP compared with HA injections on patients with a proximal patellar tendinopathy. Methods. … Continued

Efficacy of ultrasound-guided hyaluronic acid injections in achilles and patellar tendinopathies: a prospective multicentric clinical trial

Background. Achilles and patellar tendinopathies are common causes of chronic pain and functional impairment. Conservative management can be effective, but it is time-consuming and it requires intensive patient compliance. Hyaluronic acid (HA) is a key component of the extracellular matrix and its anti-inflammatory, lubricant and analgesic properties are well documented in osteoarthritis. Growing pre-clinical studies … Continued