SUMMARY
Background. Autologous platelet-rich plasma (PRP) therapy has been applied in treatment of medial or lateral elbow epicondylitis; however, its efficacy is variable possibly due to differences in PRP platelet or neutrophil concentrations. We prepared neutrophil-reduced PRP with optimized platelet concentrations, and investigated therapeutic effects of the platelet-optimized PRP for elbow epicondylitis.
Methods. We treated 65 elbows of 60 patients (9 women and 51 men) with mean age of 50 years. Neutrophil-reduced PRP with optimized platelet concentrations were used in 41 lateral epicondylitis and 24 medial epicondylitis cases. Visual analogue pain scores (VAS) and modified Mayo Elbow Performance scores (MEPS) were obtained for each elbow at pre-PRP therapy and at 3, 6 or 12 months after the treatment.
Results. In 57 enthesopathies (34 lateral and 23 medial elbow epicondylitis), VAS or modified MEPS values at 3 months after treatment were significantly lower or higher, respectively, than those obtained before treatment; and this tendency was more manifested at 6 and 12 months after treatment. The PRP therapies were relatively less effective in 3 cases with complete tears at insertional site(s) of common tendons, 3 cases of lateral epicondylitis with synovial fringes, one with entrapment of the posterior interosseous nerve and in one welfare-reliant patient. Following the treatment with platelet-optimized PRP, VAS or modified MEPS values were lower or higher, respectively, than those reported in previous studies where not optimized PRP preparations were used.
Conclusions. The platelet-optimized PRP therapy is effective for treatment of enthesopathy in elbow epicondylitis and this efficacy is higher than with PRP therapies without optimized platelet concentrations.
Neutrophil-Reduced Platelet Rich Plasma with Optimal Platelets Concentrations for Epicondylitis of the Elbow
M. Yoshida, M. Saito
Case report, 457-462
Keywords: enthesopathy, lateral elbow epicondylitis, medial elbow epicondylitis, optimal concentration of platelets, platelet rich plasma,
Table of Content: Vol. 11 (No.3) 2021 July/September
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Postural Stability in Men with Anterior Cruciate and Bicruciate Ligament Knee Injury
E. Kamińska, T. Piontek, M. Wiernicka, M. Goliwąs, J. Lewandowski, K. AdamczewskaOriginal Article, 367-375 -
Demographic and Clinical Factors Predict Focused Shockwave Therapy Results on Patients With Plantar Fasciitis. A Multilevel Analysis
A. Vertuccio, D. Perugia, R. M. Lanzetti, A. Massimiani, A. Lacopo, S. M. Nusca, R. Baldini, F. Santoboni, E. Latini, M. Vetrano, M. C. VulpianiOriginal Article, 376-382 -
Diagnostic Accuracy of Physical Tests and Imaging Techniques in Patients with Shoulder Impingement Syndrome
M. Lorusso, E. Mastrangelo, G. Garofalo, D. Ristori, F. BrindisinoReview, 383-408 -
The Immediate Effect of Muscle Energy Technique and Whole Body Vibration on Hamstring Muscle Flexibility and Stiffness in Healthy Young Females
M. Azizi, A. Shadmehr, K. Malmir, N. Qotbi, Z. Khazaei PourOriginal Article, 409-415 -
A Single-blind Randomised Trial of Intra-Articular Hyaluronic Acid, Hypertonic Saline, and Physiotherapy in Knee Osteoarthritis
E. Taftian, S. Azizi, A. Dadarkhah, N. Maghbouli, S. Najafi, Z. Reza Soltani, A. KhavandegarOriginal Article, 416-426 -
Osseous Ankle Morphology and Recurrent Lateral Sprains: a Case-Control Study
V. Nabi, M. N. Doral, O. Bilge, G. Huri, F. Familiari, J. NylandOriginal Article, 427-432 -
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A. De Carli, E. Gaj, S. M. Pagnotta, O. Picconi, A. FerrettiOriginal Article, 433-438 -
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D. Dissanguan, P. Sitilertpisan, L. H. Joseph, A. PaungmaliOriginal Article, 439-448 -
Association of Regional Bioelectrical Phase Angle with Physical Performance: a Pilot Study in Elite Rowers
F. Campa, G. Mascherini, G. Polara, D. Chiodo, L. StefaniOriginal Article, 449-456 -
Neutrophil-Reduced Platelet Rich Plasma with Optimal Platelets Concentrations for Epicondylitis of the Elbow
M. Yoshida, M. SaitoCase report, 457-462 -
Photobiomodulation in Temporomandibular Dysfunction: a Systematic Review
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A. Arumugam, A. M. Javed, S. F. Mohammad, R. M. Mallash, L. A. Aoni, M. K. Aljannan, M. Alkandri, T. M. ShoushaOriginal Article, 507-516 -
Short-Term Outcome of Focused Shock Wave Therapy for Sural Myofascial Pain Syndrome associated with Plantar Fasciitis: a Randomized Controlled Trial
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R. R. V. Melo, M. S. Cerqueira, G. M. Barbosa, A. L. B. A. Laurentino, I. M. Franca, T. O. Souza, W. H. Brito VieiraOriginal Article, 536-546 -
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